Antidepressants and antipsychotics could be alternatives to opioids, study finds
The study examined common pain medications like acetaminophen and ibuprofen, but also the promise of other drugs like ketamine and antipsychotics for pain relief. Photograph: Westend61/Getty ImagesView image in fullscreenThe study examined common pain medications like acetaminophen and ibuprofen, but also the promise of other drugs like ketamine and antipsychotics for pain relief. “The desire to reduce opioids shouldn’t come at the expense of under-treating pain,” Shanmugam said.However, alternatives can also have an important role as physicians have become increasingly aware of possible long-term consequences.
- ▪The study examined common pain medications like acetaminophen and ibuprofen, but also the promise of other drugs like ketamine and antipsychotics for pain relief.
- ▪Photograph: Westend61/Getty ImagesView image in fullscreenThe study examined common pain medications like acetaminophen and ibuprofen, but also the promise of other drugs like ketamine and antipsychotics for pain relief.
- ▪“The desire to reduce opioids shouldn’t come at the expense of under-treating pain,” Shanmugam said.However, alternatives can also have an important role as physicians have become increasingly aware of possible long-term consequences.
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| Original publisher | the Guardian |
| Canonical URL | https://www.theguardian.com/society/2026/jun/14/other-medications-opioids-alternatives-study |
| Publication time | Sun, 14 Jun 2026 22:45:38 +0000 |
| Retrieval time | 2026-06-14T23:07:33.529Z |
| Last seen | 2026-06-14T23:07:33.529Z |
| Headline source | Publisher (no WeSearch rewrite) |
| Excerpt source | publisher body |
| Excerpt method | First ~120 words (~800 chars) of extracted publisher body, fair-use limited. |
| Summary | WeSearch · cerebras-chat (WeSearch summarizer) |
| Summary source text | contentText |
| Citation coverage | Summary is a WeSearch-generated derivative; primary citation is the original publisher URL. |
| Cluster | lfZ5g24-_pD_ |
| Cluster logic | Grouped by semantic title/content similarity across sources within a rolling window. Same-publisher template collisions are excluded from coverage comparison. |
| Ranking reason | Story pages are not engagement-ranked. Hub feeds use recency, with optional source-diversified chronological ordering (cap consecutive stories per source). No personalized ranking. |
| Publisher visit | Yes — open original |
| Substitutes article? | No — link-out required for full text |
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| Indexing | May the item be indexed (stored, ranked, made findable)? | Allowed |
| Snippet | May a short excerpt of the publisher's text be shown? | Allowed |
| AI summary | May WeSearch generate its own short summary of the article? | Limited |
| Retrieval / RAG | May the content be exposed for third-party retrieval-augmented generation? | Not asserted |
| Model training | May the content be used to train AI models? | Not asserted |
| Commercial reuse | May the content be reused commercially? | Not permitted |
Basis: Derived from the published RSS/Atom feed. Contact: [email protected]. Reviewed: 2026-07-24.
Opening excerpt (first ~120 words) tap to expand
The study examined common pain medications like acetaminophen and ibuprofen, but also the promise of other drugs like ketamine and antipsychotics for pain relief. Photograph: Westend61/Getty ImagesView image in fullscreenThe study examined common pain medications like acetaminophen and ibuprofen, but also the promise of other drugs like ketamine and antipsychotics for pain relief. Photograph: Westend61/Getty ImagesOpioidsAntidepressants and antipsychotics could serve as alternatives to opioids, study findsMedications that target depression, anxiety and poor sleep could help treat pain without opioids’ addictive propertiesHannah Harris GreenSun 14 Jun 2026 08.00 EDTLast modified on Sun 14 Jun 2026 08.01 EDTSharePrefer the Guardian on GoogleA range of other medications could serve as…
Excerpt limited to ~120 words for fair-use compliance. The full article is at the Guardian.
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