Genital Lesions Most Common Sign of CCD
A recent study found that genital lesions are the most common sign of cutaneous Crohn's disease (CCD), particularly among female patients. The study reviewed records of 57 patients, most of whom had concurrent intestinal Crohn's disease. Biologic therapies were associated with higher rates of resolution in patients treated before their CCD diagnosis.
- ▪The study involved 57 patients treated at nine US academic centers between 2000 and 2020.
- ▪70% of patients had intestinal Crohn's disease at the time of CCD diagnosis.
- ▪Biologic or small-molecule inhibitor therapy was used in 82% of patients, with TNF-alpha inhibitors being the most common.
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TOPLINE:Most patients with cutaneous Crohn’s disease (CCD) in a US study were female and had concurrent intestinal Crohn’s disease and genital skin involvement, and biologic or small-molecule inhibitor therapies were associated with high rates of partial or complete resolution.METHODOLOGY:Researchers retrospectively reviewed records of 57 adult and pediatric patients (age range at diagnosis, 10-57 years; 81% female; 81% White, 9% Black, 5% Hispanic, 2% Asian) with CCD treated at nine US academic centers between 2000 and 2020.
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