Nationals vs. Guardians prediction, odds, time: 2026 MLB picks for Tuesday, May 26 from proven model
The Cleveland Guardians are set to face the Washington Nationals in the second game of their interleague series. The Guardians, currently leading the AL Central, have a strong pitching lineup, while the Nationals are known for their high-scoring games despite struggling defensively. Betting odds favor the Guardians slightly, with predictions suggesting a high-scoring matchup based on recent performances.
- ▪The Guardians are 32-24 and lead the AL Central by 3.5 games.
- ▪The Nationals are 28-27 and rank first in MLB for scoring but last in runs allowed.
- ▪Left-hander Joey Cantillo will start for the Guardians, while Cade Cavalli will pitch for the Nationals.
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| Original publisher | CBS Sports |
| Canonical URL | https://www.cbssports.com/mlb/news/nationals-guardians-prediction-odds-time-2026-mlb-picks-tuesday-may-26-best-bets/ |
| Publication time | Tue, 26 May 2026 20:56:38 +0000 |
| Retrieval time | 2026-05-26T21:07:54.543Z |
| Last seen | 2026-05-26T21:07:54.543Z |
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| Cluster | 0OVHKBxAwmK4 · 2 stories |
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Basis: Derived from the published RSS/Atom feed. Contact: [email protected]. Reviewed: 2026-07-24.
Opening excerpt (first ~120 words) tap to expand
Jose Ramirez and the AL Central-leading Cleveland Guardians host C.J. Abrams the upstart Washington Nationals on Tuesday in the second game of a three-game interleague series. The Guardians (32-24) are once again successful behind their pitching, while the Nationals (28-27) have been a wild bunch, tops in MLB in scoring and dead-last in runs allowed. Left-hander Joey Cantillo (4-1, 3.05 ERA) gets the start for the Guardians, who start the day 3.5 games ahead of the White Sox in the Central. The Nationals, second to the Braves in the NL East, counter with Cade Cavalli (2-3, 3.86). First pitch from Progressive Park in Cleveland is set for 6:10 p.m. ET. Cleveland is a slight -132 favorite on the money line (risk $132 to win $100) while Washington is at +111 in the latest Nationals vs.
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