Nearly 10% AxSpA Patients Meet Difficult-to-Manage Criteria
A recent study found that 9.1% of patients with axial spondyloarthritis (axSpA) meet the criteria for difficult-to-manage disease. Among these, 2.2% were classified as having treatment-refractory axSpA. The study highlights the need for integrated care approaches due to the complexity of managing these patients.
- ▪The study analyzed data from 536 axSpA patients in Toronto, Canada.
- ▪Patients with difficult-to-manage axSpA had higher disease activity compared to those without.
- ▪Higher spinal pain scores and fibromyalgia were linked to difficult-to-manage axSpA.
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| Original publisher | Medscape |
| Canonical URL | https://www.medscape.com/viewarticle/nearly-10-patients-axspa-meet-criteria-difficult-manage-2026a1000ifj?src=rss |
| Publication time | Wed, 3 Jun 2026 01:11:22 EDT |
| Retrieval time | 2026-06-03T05:41:56.797Z |
| Last seen | 2026-06-03T05:41:56.797Z |
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| Publisher visit | Yes — open original |
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| Snippet | May a short excerpt of the publisher's text be shown? | Allowed |
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| Retrieval / RAG | May the content be exposed for third-party retrieval-augmented generation? | Not asserted |
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| Commercial reuse | May the content be reused commercially? | Not permitted |
Basis: Derived from the published RSS/Atom feed. Contact: [email protected]. Reviewed: 2026-07-24.
Opening excerpt (first ~120 words) tap to expand
TOPLINE:Among patients with axial spondyloarthritis (axSpA), 9.1% fulfilled the criteria for difficult-to-manage (D2M) disease, with 2.2% meeting the criteria for treatment-refractory disease. Higher spinal pain scores and fibromyalgia were independently linked to D2M axSpA.METHODOLOGY:Researchers performed a cross-sectional analysis of prospectively collected data to determine the prevalence of D2M axSpA and identify associated factors in 536 patients with axSpA (median age, 48 years; 66% male) who attended follow-up visits between May 2024 and May 2025 at an institute in Toronto, Ontario, Canada.The Assessment of SpondyloArthritis International Society (ASAS) definitions for D2M and treatment-refractory disease were applied, with D2M defined as treatment failure with at least two…
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