Scientists discover hidden driver of aging — Simple supplement reversed brain decline
Researchers have identified a brain protein called Menin that plays a significant role in the aging process. In experiments with mice, restoring Menin levels reversed several aging-related effects, while an amino acid supplement, D-serine, improved cognitive function. This discovery highlights the hypothalamus as a central player in regulating aging and opens new avenues for potential treatments.
- ▪Menin levels decline in the hypothalamus as mice age, leading to inflammation and cognitive decline.
- ▪Restoring Menin in older mice improved memory, balance, and bone density within 30 days.
- ▪D-serine, an amino acid supplement, was found to enhance cognitive function in older mice.
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| Original publisher | ScienceDaily |
| Canonical URL | https://www.sciencedaily.com/releases/2026/05/260524012959.htm |
| Publication time | Sun, 24 May 2026 01:40:19 EDT |
| Retrieval time | 2026-05-24T05:52:31.313Z |
| Last seen | 2026-05-24T05:52:31.313Z |
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Opening excerpt (first ~120 words) tap to expand
Science News from research organizations Scientists discover hidden driver of aging — Simple supplement reversed brain decline Scientists may have found a hidden brain “aging switch” — and a simple amino acid helped reverse some of its effects in mice. Date: May 24, 2026 Source: PLOS Summary: A newly identified brain protein may play a major role in how the body ages. Researchers discovered that declining levels of Menin in the hypothalamus triggered inflammation, memory problems, bone loss, and other aging-related changes in mice. Restoring Menin reversed several of these effects, while a simple amino acid supplement called D-serine boosted cognition. The discovery opens a surprising new path for fighting age-related decline.
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