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Single-molecule tracker illuminates workings of cancer-related proteins

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Researchers at the Broad Institute have developed a new imaging technique to track cancer-related proteins in real-time. This method utilizes stable nanoparticle probes to observe the dynamics of receptor interactions within living cells. The findings could enhance drug screening and provide insights into cancer mechanisms.

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Original publisherMIT News
Canonical URLhttps://news.mit.edu/2026/single-molecule-tracker-illuminates-cancer-related-proteins-0519
Publication timeTue, 19 May 2026 11:35:00 -0400
Retrieval time2026-05-19T15:44:57.717Z
Last seen2026-05-19T15:44:57.717Z
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Basis: Derived from the published RSS/Atom feed. Contact: [email protected]. Reviewed: 2026-07-24.

Opening excerpt (first ~120 words) tap to expand

Researchers use custom-built microscopy and nanotechnology to tag and follow the activity of individual proteins in real-time. Leah Eisenstadt | Broad Institute Publication Date: May 19, 2026 Press Inquiries Press Contact: Danielle Randall Doughty Email: [email protected] Phone: (617) 258-7492 Department of Chemistry Close Caption: Peng lab member and study co-first-author João Shida prepares to image nanoparticles using the lab’s custom-built microscope. Credits: Photo: Allison Colorado/Broad Communications Previous image Next image Using a powerful single-molecule imaging method they developed, a research team from the Broad Institute of MIT and Harvard has unveiled a dynamic view of how some cancer-related proteins interact in living cells.

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