Surgery or Meds for Weight Regain After Sleeve Gastrectomy?
A study comparing conversion surgery and medication therapy for weight regain after sleeve gastrectomy found that surgery leads to greater weight loss. One-anastomosis gastric bypass showed the most significant results, with higher total weight loss and better resolution of type 2 diabetes and hypertension. The research highlights the effectiveness of surgical options over pharmacological treatments for patients experiencing recurrent weight gain.
- ▪Conversion surgery, particularly one-anastomosis gastric bypass, delivers greater and more durable weight loss than medication therapy.
- ▪Among 195 participants, those who underwent one-anastomosis gastric bypass had a mean total weight loss of 25.8%.
- ▪Resolution rates of type 2 diabetes and hypertension were significantly higher in the surgery groups compared to the medication group.
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TOPLINE:Conversion surgery, particularly one-anastomosis gastric bypass, delivers greater and more durable weight loss than medication therapy in patients with recurrent weight gain after sleeve gastrectomy.METHODOLOGY:Sleeve gastrectomy carries a notable risk for recurrent weight gain that may require revisional conversion to Roux-en-Y gastric bypass or one-anastomosis gastric bypass, procedures that are more complex than obesity medication therapy with agents such as GLP-1 receptor agonists.Researchers conducted a retrospective analysis of a prospectively maintained registry at a tertiary university hospital in Tel Aviv, Israel, to compare long-term outcomes with obesity management medications vs conversion surgery in patients treated for recurrent weight gain after sleeve gastrectomy…
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