Treat the Overlap Between Long COVID and Chronic Fatigue
A new study suggests that treatments for long COVID can benefit from approaches used for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Researchers advocate for the use of targeted therapies like beta-blockers and low-dose naltrexone to address the treatment gap for long COVID patients. Many individuals with long COVID exhibit symptoms that align closely with ME/CFS, highlighting the need for better management strategies in primary care settings.
- ▪The study published in Annals of Family Medicine emphasizes the similarity between long COVID and ME/CFS symptoms.
- ▪Researchers found that many medications effective for ME/CFS were underutilized by primary care clinicians treating long COVID.
- ▪Approximately half of those diagnosed with long COVID meet the criteria for ME/CFS, indicating a significant overlap between the two conditions.
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| Original publisher | Medscape |
| Canonical URL | https://www.medscape.com/viewarticle/physicians-are-undertreating-chronic-fatigue-they-could-2026a1000hwg?src=rss |
| Publication time | Fri, 29 May 2026 03:07:14 EDT |
| Retrieval time | 2026-05-29T07:19:58.503Z |
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In an effort to help patients with long COVID, family medicine clinicians can borrow from the treatment of another chronic syndrome, according to a new study published in Annals of Family Medicine.Symptoms of the condition often resemble myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), and researchers said clinicians should adopt targeted therapies like beta-blockers and low-dose naltrexone to bridge a treatment gap left by a lack of specialists who treat long COVID, also known as post-acute sequelae of COVID.“There are high numbers of people with long COVID who either have the full criteria with ME/CFS or symptoms of it,” said Stephanie Grach, MD, MS, an internist at the Mayo Clinic in Rochester, Minnesota, who led the new study.Both conditions are extremely similar and are…
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